Publications
Below you can find a list of our published research.
Below you can find a list of our published research.
42 results
European heart journal. Cardiovascular Imaging, Volume 24, Issue 12, 1 1 2023, Pages 1682-1689 Prognostic value of left ventricular myocardial work indices in patients with severe aortic stenosis undergoing transcatheter aortic valve replacement. Wu HW, Fortuni F, Butcher SC, van der Kley F, de Weger A, Delgado V, Jukema JW, Bax JJ, Ajmone Marsan N
Aims: Left ventricular myocardial work (LVMW) is a novel echocardiographic-based method to assess left ventricular (LV) function using pressure-strain loops taking into account LV afterload. The aim of this study was to evaluate the prognostic value of LVMW indices in patients with severe aortic stenosis (AS) undergoing transcatheter aortic valve replacement (TAVR). Methods and results: LV global work index (LV GWI), LV global constructive work (LV GCW), LV global wasted work (LV GWW), and LV gl... Abstract
Cited 1 times since 2023 (1.7 per year) source: EuropePMC
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation, Volume 31, Issue 12, 16 3 2023, Pages 473-478 National indication document and aortic valve replacement landscape in the Netherlands. Eerdekens R, van Steenbergen G, El Farissi M, Demandt J, van 't Veer M, Daeter E, Timmers L, de Weger A, Medendorp N, Tonino P, Transcatheter Heart Valve Intervention Registry Committee, Cardiothoracic Surgery Registry Committee of the Netherlands Heart Registry
Introduction: Based on European guidelines, transcatheter aortic valve implementation (TAVI) could be the therapy of choice in patients with severe aortic stenosis aged ≥ 75 years. In the Netherlands, there has been a debate between healthcare providers and the National Health Care Institute regarding reimbursement for TAVI, which resulted in an indication document that defines TAVI patients who are eligible for reimbursement. This document has been effective since 1 January 2021. Methods: We ex... Abstract
International journal of cardiology, Volume 395, 5 1 2023, Pages 131414 Impact of chronic obstructive pulmonary disease on right ventricular function and remodeling after aortic valve replacement. Myagmardorj R, Stassen J, Nabeta T, Hirasawa K, Singh GK, van der Kley F, de Weger A, Ajmone Marsan N, Delgado V, Bax JJ
Background: Both chronic obstructive pulmonary disease (COPD) and right ventricular (RV) dysfunction are common factors that have been associated with poor prognosis after aortic valve replacement (AVR). Since there is still uncertainty about the impact of COPD on RV function and dilatation in patients undergoing AVR, we sought to explore RV function and remodeling in the presence and absence of COPD as well as their prognostic implications. Methods: Patients who received surgical or transcathet... Abstract
The Annals of thoracic surgery, Volume 117, Issue 1, 14 2 2023, Pages 120-126 A Nationwide Study on Mitral Valve Repair vs Replacement for Active Endocarditis. Tomšič A, de Weger A, van der Stoel M, Klautz RJM, Palmen M, Cardiothoracic Surgery Registration Committee of the Netherlands Heart Registration
Background: Real-world evidence supporting the reproducibility and superiority of valve repair over replacement in active mitral valve infective endocarditis is lacking. Methods: Data from a prospective nationwide database, including all cardiac surgical procedures in The Netherlands, were used. Adult patients undergoing primary mitral valve intervention who had a diagnosis of active infective endocarditis and who underwent surgery between 2013 and 2020 were included. Survival analysis was perfo... Abstract
Cited 1 times since 2023 (0.8 per year) source: EuropePMC
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, Volume 25, Issue 1, 1 1 2023, Pages 49-58 Mobile health vs. standard care after cardiac surgery: results of The Box 2.0 study. Biersteker TE, Boogers MJ, Schalij MJ, Penning de Vries BBL, Groenwold RHH, van Alem AP, de Weger A, van Hof N, Treskes RW
Aims: Postoperative atrial fibrillation (POAF) is a common complication of cardiac surgery, yet difficult to detect in ambulatory patients. The primary aim of this study is to investigate the effect of a mobile health (mHealth) intervention on POAF detection after cardiac surgery. Methods and results: We performed an observational cohort study among 730 adult patients who underwent cardiac surgery at a tertiary care hospital in The Netherlands. Of these patients, 365 patients received standard c... Abstract
The American journal of cardiology, Volume 190, 20 3 2022, Pages 41-47 Association Between Chronic Obstructive Pulmonary Disease and All-Cause Mortality After Aortic Valve Replacement for Aortic Stenosis. Myagmardorj R, Nabeta T, Hirasawa K, Singh GK, van der Kley F, de Weger A, Ajmone Marsan N, Bax JJ, Delgado V
Chronic obstructive pulmonary disease (COPD) and aortic stenosis (AS) are the most common diseases in which age plays a major role in the increase of their prevalence and when they co-exist, the outcomes prognosis worsens significantly. The aim of the present study was to evaluate the association between pulmonary functional parameters and all-cause mortality after aortic valve replacement (transcatheter or surgical). A total of 400 patients with severe AS and preoperative pulmonary functional t... Abstract
The American journal of cardiology, Volume 186, 29 5 2022, Pages 176-180 Prognostic Value of Nonalcoholic Fatty Liver Disease in Patients With Severe Aortic Stenosis Who Underwent Transcatheter Aortic Valve Implantation. Nabeta T, Myagmardorj R, Hirasawa K, Singh GK, van der Kley F, de Weger A, Knuuti J, Bax JJ, Marsan NA, Delgado V
Nonalcoholic fatty liver disease (NAFLD) is associated with an increased risk of cardiovascular events. Although the association between NAFLD and aortic valve sclerosis has been described, the prevalence and prognostic implications of NAFLD among patients with severe aortic stenosis (AS) have not been described. In addition, the effect of the presence of severe tricuspid regurgitation (TR) on the prevalence of NAFLD remains unexplored. Accordingly, we investigated the prognostic implications of... Abstract
Cited 1 times since 2022 (0.5 per year) source: EuropePMC
The American journal of cardiology, Volume 179, 15 3 2022, Pages 64-69 Effects of Left Bundle Branch Block and Pacemaker Implantation on Left Ventricular Systolic Function After Transcatheter Aortic Valve Implantation. Dolci G, Singh GK, Wang X, van der Kley F, de Weger A, Bootsma M, Ajmone Marsan N, Bax JJ, Delgado V
Permanent pacemaker implantation (PPI) and left bundle branch block (LBBB) frequency after transcatheter aortic valve implantation (TAVI) and their effect on left ventricular ejection fraction (LVEF) remain controversial. We evaluated the incidence of PPI and new-onset LBBB after TAVI and their impact on LVEF at 6-month follow-up. Moreover, the impact of right ventricular (RV) pacing burden on changes in LVEF after TAVI was analyzed. The electrocardiograms of 377 patients (age 80 ± 7 years, 52%... Abstract
Cited 1 times since 2022 (0.5 per year) source: EuropePMC
The American journal of cardiology, Volume 173, 1 1 2022, Pages 48-55 Meta-Analysis of Bilateral Versus Single Internal Thoracic Artery Grafting in Patients ≥70 Years of Age. Mulder BS, Candura D, Schoones JW, Etnel JRG, Schouten GN, de Weger A, Tomšič A, Klautz RJM
The optimal choice of graft material in patients ≥70 years of age undergoing coronary artery bypass grafting remains unknown. A systematic review of literature was conducted by searching PubMed, Embase, Web of Science, and Cochrane Library databases for original publications that compared bilateral internal thoracic artery (BITA) grafting with single internal thoracic artery grafting in patients ≥70 years of age. Data were extracted by 2 independent investigators and meta-analyzed with the use o... Abstract
Heart, lung & circulation, Volume 30, Issue 12, 7 1 2021, Pages e129-e130 Reversal of Femoral Vein Pulsatility Due to Severe Tricuspid Regurgitation After Transcatheter Tricuspid Valve-in-Valve Implantation: A "Wave Dissipation" Effect. Pereira AR, van der Kley F, Montero-Cabezas JM, de Weger A, Delgado V
Cited 20 times since 2020 (5.7 per year) source: Scopus
Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography, Volume 34, Issue 3, 9 2 2020, Pages 257-266 Left Ventricular Myocardial Work in Patients with Severe Aortic Stenosis. Fortuni F, Butcher SC, van der Kley F, Lustosa RP, Karalis I, de Weger A, Priori SG, van der Bijl P, Bax JJ, Delgado V, Ajmone Marsan N
Background: Left ventricular myocardial work (LVMW) is a novel method to assess left ventricular (LV) function using pressure-strain loops that takes into consideration LV afterload. The estimation of LV afterload in patients with severe aortic stenosis (AS) may be challenging, and no study so far has investigated LVMW in this setting. The aim of this study was to develop a method to calculate LVMW in patients with severe AS and to analyze its relationship with heart failure symptoms. Methods: I... Abstract
Cited 5 times since 2019 (1.1 per year) source: Scopus
The American journal of cardiology, Volume 125, Issue 6, 27 4 2019, Pages 948-955 Prognostic Influence of Feature Tracking Multidetector Row Computed Tomography-Derived Left Ventricular Global Longitudinal Strain in Patients with Aortic Stenosis Treated With Transcatheter Aortic Valve Implantation. Gegenava T, van der Bijl P, Vollema EM, van der Kley F, de Weger A, Hautemann D, Reiber JHC, Ajmone Marsan N, Bax JJ, Delgado V
Computed tomography plays a central role in the evaluation of patients with severe aortic stenosis who underwent transcatheter aortic valve implantation (TAVI). Advances in left ventricular (LV) analysis with multidetector row computed tomography (MDCT) permit measurement of LV global longitudinal strain (GLS). The present study aimed at evaluating the association between feature tracking (FT) MDCT derived LV GLS and all-cause mortality in patients treated with TAVI. A total of 214 patients with... Abstract
Cited 7 times since 2019 (1.6 per year) source: Scopus
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, Volume 56, Issue 6, 1 1 2019, Pages 1117-1123 Reinterventions after freestyle stentless aortic valve replacement: an assessment of procedural risks. Schneider AW, Hazekamp MG, Versteegh MIM, de Weger A, Holman ER, Klautz RJM, Bruggemans EF, Braun J
Objectives: Repeat aortic valve interventions after previous stentless aortic valve replacement (AVR) are considered technically challenging with an increased perioperative risk, especially after full-root replacement. We analysed our experience with reinterventions after stentless AVR. Methods: A total of 75 patients with previous AVR using a Freestyle stentless bioprosthesis (31 subcoronary, 15 root-inclusion and 29 full-root replacement) underwent reintervention in our centre from 1993 until... Abstract
Cited 8 times since 2019 (1.8 per year) source: Scopus
Journal of cardiovascular computed tomography, Volume 14, Issue 3, 1 1 2019, Pages 240-245 Feature tracking computed tomography-derived left ventricular global longitudinal strain in patients with aortic stenosis: a comparative analysis with echocardiographic measurements. Gegenava T, van der Bijl P, Hirasawa K, Vollema EM, van Rosendael A, van der Kley F, de Weger A, Hautemann DJ, Reiber JHC, Ajmone Marsan N, Bax JJ, Delgado V
Background: Left ventricular (LV) systolic function is a prognostic factor in patients with severe aortic stenosis (AS). Multi-detector row computed tomography (MDCT) data are key in the evaluation of patients undergoing transcatheter aortic valve implantation (TAVI) and when acquired retrospectively, LV systolic function can be assessed. Novel software permits assessment of LV global longitudinal strain (GLS) from MDCT data. Objectives: The present study investigated the feasibility of feature... Abstract
Cited 9 times since 2019 (1.9 per year) source: Scopus
The American journal of cardiology, Volume 124, Issue 8, 30 5 2019, Pages 1239-1245 One-Year Follow-Up of Conduction Abnormalities After Transcatheter Aortic Valve Implantation With the SAPIEN 3 Valve. Dolci G, Vollema EM, van der Kley F, de Weger A, Ajmone Marsan N, Delgado V, Bax JJ
Long-term evolution of new-onset conduction abnormalities and need of permanent pacemaker implantation (PPI) after transcatheter aortic valve implantation (TAVI) have not been extensively evaluated. We describe the incidence and time course of new conduction abnormalities and the rate of PPI with the new-generation transcatheter aortic valve prosthesis Edwards SAPIEN 3 (S3). In total, 266 patients with severe aortic stenosis who underwent TAVI were retrospectively analyzed. Twelve-lead electroca... Abstract
Cited 5 times since 2019 (1 per year) source: Scopus
Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography, Volume 32, Issue 9, 13 2 2019, Pages 1058-1066.e2 Changes in Left Ventricular Global Longitudinal Strain after Transcatheter Aortic Valve Implantation according to Calcification Burden of the Thoracic Aorta. Gegenava T, Vollema EM, van Rosendael A, Abou R, Goedemans L, van der Kley F, de Weger A, Ajmone Marsan N, Bax JJ, Delgado V
Background: After transcatheter aortic valve replacement (TAVR), changes in left ventricular (LV) function are partly influenced by the vascular afterload. The burden of thoracic aorta calcification is a component of vascular afterload. Objective: To assess changes in LV systolic function measured with global longitudinal strain (GLS) in relation to the burden of thoracic aorta calcification in patients with severe aortic stenosis treated with TAVR. Methods: Calcification of the thoracic aorta w... Abstract
Cited 14 times since 2019 (2.7 per year) source: Scopus
The Canadian journal of cardiology, Volume 35, Issue 6, 21 3 2019, Pages 796.e9-796.e11 Percutaneous Decannulation of Femoral Venoarterial ECMO Cannulas Using MANTA Vascular Closure Device. Montero-Cabezas JM, van der Meer RW, van der Kley F, Elzo Kraemer CV, López Matta JE, Schalij MJ, de Weger A
Extracorporeal membrane oxygenation (ECMO) has been increasingly used in the treatment of refractory cardiac arrest and postarrest cardiogenic shock. We propose a technique for percutaneous decannulation of femoral venoarterial ECMO cannulas by using the MANTA vascular closure device, designed to close large-bore arteriotomies. This technique significantly simplifies the decannulation and might diminish the potential complications caused by the standard surgical removal. Abstract
Cited 6 times since 2018 (1.1 per year) source: Scopus
JACC. Cardiovascular imaging, Volume 12, Issue 1, 15 3 2018, Pages 216-217 Prognostic Value of Thoracic Aorta Calcification Burden in Patients Treated With TAVR. Gegenava T, Vollema EM, Abou R, Goedemans L, van Rosendael A, van der Kley F, de Weger A, Ajmone Marsan N, Bax JJ, Delgado V
Cited 13 times since 2017 (2 per year) source: Scopus
The American journal of cardiology, Volume 121, Issue 1, 10 2 2017, Pages 86-93 Influence of the Quantity of Aortic Valve Calcium on the Agreement Between Automated 3-Dimensional Transesophageal Echocardiography and Multidetector Row Computed Tomography for Aortic Annulus Sizing. Podlesnikar T, Prihadi EA, van Rosendael PJ, Vollema EM, van der Kley F, de Weger A, Ajmone Marsan N, Naji F, Fras Z, Bax JJ, Delgado V
Accurate aortic annulus sizing is key for selection of appropriate transcatheter aortic valve implantation (TAVI) prosthesis size. The present study compared novel automated 3-dimensional (3D) transesophageal echocardiography (TEE) software and multidetector row computed tomography (MDCT) for aortic annulus sizing and investigated the influence of the quantity of aortic valve calcium (AVC) on the selection of TAVI prosthesis size. A total of 83 patients with severe aortic stenosis undergoing TAV... Abstract
Cited 82 times since 2017 (11.5 per year) source: Scopus
European heart journal, Volume 38, Issue 16, 1 1 2017, Pages 1207-1217 Transcatheter aortic valve thrombosis: the relation between hypo-attenuated leaflet thickening, abnormal valve haemodynamics, and stroke. Vollema EM, Kong WKF, Katsanos S, Kamperidis V, van Rosendael PJ, van der Kley F, de Weger A, Ajmone Marsan N, Delgado V, Bax JJ
Aims: The presence of hypo-attenuated leaflet thickening (HALT) and/or reduced leaflet motion on multi-detector row computed tomography (MDCT) has been proposed as a possible marker for early transcatheter aortic valve thrombosis. However, its association with abnormal valve haemodynamics on echocardiography (another potential marker of thrombosis) and clinical outcomes (stroke) remains unclear. The present study evaluated the prevalence of HALT on MDCT and abnormal valve haemodynamics on echoca... Abstract